MiADMSA minimizes arsenic induced bone degeneration in Sprague Dawley rats
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چکیده
منابع مشابه
Serum Acetyl Cholinesterase as a Biomarker of Arsenic Induced Neurotoxicity in Sprague-Dawley Rats
Arsenic is an environmental toxicant, and one of the major mechanisms by which it exerts its toxic effect is through an impairment of cellular respiration by inhibition of various mitochondrial enzymes, and the uncoupling of oxidative phosphorylation. Most toxicity of arsenic results from its ability to interact with sulfhydryl groups of proteins and enzymes, and to substitute phosphorus in a v...
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in this study,14 female sprague-dawley rats 55 days old were randomly divided into two control and experimental groups.2ml of 7,12-dimethylbenz{a} anthracene (DMBA) solution(20 mg of DMBA dissolved in 2 ml of corn oil) and 2 ml corn oil was eaten to each animal of test and control group respectively.tumor development was examined by milk line palpation once every week.during 3-5 months followin...
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Background & Objective: One of the most serious health problems is osteoporosis and it is mandatory to find preventive methods to confront this difficulty. Non-pharmacological methods are in priority due to less side effects. This study investigated the effect of treadmill running exercise on bone microarchitectures in female osteoporotic rats induced by ovariectomy. Materials & Methods: 30 rat...
متن کاملRenalase Protects against Contrast-Induced Nephropathy in Sprague-Dawley Rats
BACKGROUND Contrast-induced nephropathy (CIN) is the third leading cause of hospital-acquired acute renal failure. Oxidative stress, apoptosis and inflammation play crucial roles in CIN. Renalase is a newly discovered monoamine oxidase from the kidney. We hypothesize that renalase could protect against CIN through anti-oxidation, anti-inflammation and anti-apoptosis pathways. METHODS We teste...
متن کاملSulodexide Protects Contrast-Induced Nephropathy in Sprague-Dawley Rats.
BACKGROUND Sulodexide is a powerful antithrombin agent with reno-protective property. However, whether it has beneficial effects on Contrast-Induced Nephropathy (CIN) remained elusive. In the current study, we evaluated the therapeutic effects of Sulodexide on CIN and investigated the potential mechanisms. METHODS CIN model was induced by intravenous injection of indomethacin, followed by Iov...
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ژورنال
عنوان ژورنال: Emerging Contaminants
سال: 2020
ISSN: 2405-6650
DOI: 10.1016/j.emcon.2020.06.001